Pathway Commons

Pathway Guide

Pathway Commons
  1. Guide
  2. Case Studies

Case Studies

Recent highlights from the literature using interaction and pathway analyses

Pathway Enrichment Analysis


Press Pause

Enrichment analysis identifies transcriptional elongation factors as key vulnerabilities for glioblastoma growth in vivo

Miller et al. Nature 547 (2017)

Dark Matter

In brain tumors, pathway analysis links epigenetic alterations to pathways targeted by chemotherapy in hematopoietic malignancies

Mack et al. Nature (2014)

Pathway Commons


Cause and Effect

Winners of the DREAM 8 challenge to infer causality in a signaling network rely on pathways extracted from Pathway Commons

Hill et al. Nat Methods (2016)

Forever Young

Geneticists use Pathway Commons data to link gene implicated in leukemia to well-studied oxidative-stress pathways that maintain stem-cell renewal

Santos et al Nature (2014)